Louisiana State University is a major Moodle user and has been growing it’s own documentation for Moodle over the past few years. “GROK” as the documentation and tutorials are known, includes information about LSU’s own Moodle (and why), easy how to tips for managing classrooms (which translate to other Moodle users as well) and some handy categorization and organization of the materials for easy access.
Check out the LSU GROK to see how state flagship university manages their Moodle: http://moodle.grok.lsu.edu/.
You might be interested in their video tutorials as well: http://moodle.grok.lsu.edu/article.aspx?articleid=13080. The videos cover information such as accessing Moodle through a myMoodle page, using discussion forums and uploading files to Moodle and classrooms/assignments.